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Stabilizing HIV-1 envelope glycoprotein trimers to induce neutralizing antibodies

An effective HIV-1 vaccine probably will need to be able to induce broadly neutralizing HIV-1 antibodies (bNAbs) in order to be efficacious. The many bNAbs that have been isolated from HIV-1 infected patients illustrate that the human immune system is able to elicit this type of antibodies. The eluc...

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Detalles Bibliográficos
Autores principales: Torrents de la Peña, Alba, Sanders, Rogier W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134781/
https://www.ncbi.nlm.nih.gov/pubmed/30208933
http://dx.doi.org/10.1186/s12977-018-0445-y