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An exploratory study examining how nano-liquid chromatography–mass spectrometry and phosphoproteomics can differentiate patients with advanced fibrosis and higher percentage collagen in non-alcoholic fatty liver disease

BACKGROUND: Non-alcoholic steatohepatitis (NASH) is among the leading causes of liver disease worldwide. It is increasingly recognized that the phenotype of NASH may involve a number of different pathways, of which each could become important therapeutic targets. The aim of this study is to use high...

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Detalles Bibliográficos
Autores principales: Younossi, Zobair M., Karrar, Azza, Pierobon, Mariaelena, Birerdinc, Aybike, Stepanova, Maria, Abdelatif, Dinan, Younoszai, Zahra, Jeffers, Thomas, Felix, Sean, Jeiran, Kianoush, Hodge, Alex, Zhou, Weidong, Monge, Fanny, Alaparthi, Lakshmi, Chandhoke, Vikas, Goodman, Zachary D., Petricoin, Emanuel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134795/
https://www.ncbi.nlm.nih.gov/pubmed/30205811
http://dx.doi.org/10.1186/s12916-018-1136-1