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NKX2-2 Suppresses Osteosarcoma Metastasis and Proliferation by Downregulating Multiple Target Genes

Osteosarcoma is the most common primary malignant bone tumor. However, our understanding of the molecular mechanism underlying its pathogenesis is incomplete. Studies have shown that aberrant expression of NK homeobox (NKX) genes may be involved in the oncogenesis of various cancers. Here, through m...

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Detalles Bibliográficos
Autores principales: Chen, Huiming, Liu, Wenqiang, Zhong, Li, Liao, Dan, Zhang, Ruhua, Kang, Tiebang, Wu, Yuanzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134811/
https://www.ncbi.nlm.nih.gov/pubmed/30210629
http://dx.doi.org/10.7150/jca.26382