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Inhibition of Transient Receptor Potential Vanilloid 6 channel, elevated in human ovarian cancers, reduces tumour growth in a xenograft model

Background: Transient Receptor Potential Vanilloid 6 (TRPV6), a non-voltage gated calcium channel, is implicated in malignancies and correlates with Gleason scores in prostate cancer and with poor prognosis in breast cancer. Data on the TRPV6 status of ovarian malignancies has not received significa...

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Detalles Bibliográficos
Autores principales: Xue, Hui, Wang, Yuzhuo, MacCormack, Tyson J., Lutes, Tyler, Rice, Christopher, Davey, Michelle, Dugourd, Dominique, Ilenchuk, T. Toney, Stewart, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134823/
https://www.ncbi.nlm.nih.gov/pubmed/30210643
http://dx.doi.org/10.7150/jca.20639