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Intragland Shh gene delivery mitigated irradiation-induced hyposalivation in a miniature pig model

Irreversible hypofunction of salivary glands is common in head and neck cancer survivors treated with radiotherapy and can only be temporarily relieved with current treatments. We found recently in mouse models that transient activation of Hedgehog pathway following irradiation rescued salivary glan...

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Detalles Bibliográficos
Autores principales: Hu, Liang, Zhu, Zhao, Hai, Bo, Chang, Shimin, Ma, Linsha, Xu, Yipu, Li, Xiangchun, Feng, Xiaoyu, Wu, Xiaoshan, Zhao, Qingguo, Qin, Lizheng, Wang, Jingsong, Zhang, Chunmei, Liu, Fei, Wang, Songlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134926/
https://www.ncbi.nlm.nih.gov/pubmed/30214623
http://dx.doi.org/10.7150/thno.26509