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Anti-HER2 functionalized graphene oxide as survivin-siRNA delivery carrier inhibits breast carcinoma growth in vitro and in vivo

BACKGROUND: The success of gene therapy is mostly dependent on the development of gene carrier. Graphene oxide (GO) possesses excellent aqueous solubility and biocompatibility, which is important for its biochemical and medical applications. Our previous work proved that GO can deliver siRNA into ce...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoli, Sun, Qi, Cui, Chunying, Li, Jing, Wang, Yifan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135080/
https://www.ncbi.nlm.nih.gov/pubmed/30233146
http://dx.doi.org/10.2147/DDDT.S169430