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Macrocyclic lactones inhibit nasopharyngeal carcinoma cells proliferation through PAK1 inhibition and reduce in vivo tumor growth

PURPOSE: The Epstein–Barr virus (EBV)-associated cancer nasopharyngeal carcinoma (NPC) is rare in Europe and North America but is a real public health problem in some regions of the world, such as southern Asia, North Africa, and for Inuit populations. Due to the anatomy and location of the nasophar...

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Detalles Bibliográficos
Autores principales: Gallardo, Franck, Mariamé, Bernard, Gence, Remi, Tilkin-Mariamé, Anne-Francoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135081/
https://www.ncbi.nlm.nih.gov/pubmed/30233143
http://dx.doi.org/10.2147/DDDT.S172538