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A novel method of using Deep Belief Networks and genetic perturbation data to search for yeast signaling pathways

Perturbing a signaling system with a serial of single gene deletions and then observing corresponding expression changes in model organisms, such as yeast, is an important and widely used experimental technique for studying signaling pathways. People have developed different computational methods to...

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Detalles Bibliográficos
Autores principales: Lu, Songjian, Fan, Xiaonan, Chen, Lujia, Lu, Xinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135403/
https://www.ncbi.nlm.nih.gov/pubmed/30208101
http://dx.doi.org/10.1371/journal.pone.0203871