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A novel method of using Deep Belief Networks and genetic perturbation data to search for yeast signaling pathways
Perturbing a signaling system with a serial of single gene deletions and then observing corresponding expression changes in model organisms, such as yeast, is an important and widely used experimental technique for studying signaling pathways. People have developed different computational methods to...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135403/ https://www.ncbi.nlm.nih.gov/pubmed/30208101 http://dx.doi.org/10.1371/journal.pone.0203871 |