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Computational prediction of changes in brain metabolic fluxes during Parkinson’s disease from mRNA expression
BACKGROUND: Parkinson’s disease is a widespread neurodegenerative disorder which affects brain metabolism. Although changes in gene expression during disease are often measured, it is difficult to predict metabolic fluxes from gene expression data. Here we explore the hypothesis that changes in gene...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135490/ https://www.ncbi.nlm.nih.gov/pubmed/30208076 http://dx.doi.org/10.1371/journal.pone.0203687 |