GLK-IKKβ signaling induces dimerization and translocation of the AhR-RORγt complex in IL-17A induction and autoimmune disease

Retinoic-acid-receptor-related orphan nuclear receptor γt (RORγt) controls the transcription of interleukin-17A (IL-17A), which plays critical roles in the pathogenesis of autoimmune diseases. Severity of several human autoimmune diseases is correlated with frequencies of germinal center kinase–like...

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Detalles Bibliográficos
Autores principales: Chuang, Huai-Chia, Tsai, Ching-Yi, Hsueh, Chia-Hsin, Tan, Tse-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135549/
https://www.ncbi.nlm.nih.gov/pubmed/30214937
http://dx.doi.org/10.1126/sciadv.aat5401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135549/
https://www.ncbi.nlm.nih.gov/pubmed/30214937
http://dx.doi.org/10.1126/sciadv.aat5401

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