Alendronate-induced disruption of actin cytoskeleton and inhibition of migration/invasion are associated with cofilin downregulation in PC-3 prostate cancer cells

Bisphosphonates are used for prevention of osteoporosis and metastatic bone diseases. Anti-invasive effects on various cancer cells have also been reported, but the mechanisms involved are not well-understood. We investigated the effects of the nitrogen-containing bisphosphonate alendronate (ALN) on...

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Detalles Bibliográficos
Autores principales: Virtanen, Sanna S., Ishizu, Tamiko, Sandholm, Jouko A., Löyttyniemi, Eliisa, Väänänen, H. Kalervo, Tuomela, Johanna M., Härkönen, Pirkko L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135693/
https://www.ncbi.nlm.nih.gov/pubmed/30220968
http://dx.doi.org/10.18632/oncotarget.25961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135693/
https://www.ncbi.nlm.nih.gov/pubmed/30220968
http://dx.doi.org/10.18632/oncotarget.25961

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