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The frequency of promoter DNA hypermethylation is decreased in colorectal neoplasms of familial adenomatous polyposis

Familial adenomatous polyposis (FAP) is an inherited disorder characterized by numerous colorectal adenomatous polyps with predisposition to the development of colorectal cancer (CRC). Here, we conducted genome-wide DNA methylation analysis of FAP neoplasms, including seven cancer samples and 16 ade...

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Detalles Bibliográficos
Autores principales: Takane, Kiyoko, Fukuyo, Masaki, Matsusaka, Keisuke, Ota, Satoshi, Rahmutulla, Bahityar, Matsushita, Kazuyuki, Miyauchi, Hideaki, Nakatani, Yukio, Matsubara, Hisahiro, Kaneda, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135695/
https://www.ncbi.nlm.nih.gov/pubmed/30220972
http://dx.doi.org/10.18632/oncotarget.25987