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The frequency of promoter DNA hypermethylation is decreased in colorectal neoplasms of familial adenomatous polyposis
Familial adenomatous polyposis (FAP) is an inherited disorder characterized by numerous colorectal adenomatous polyps with predisposition to the development of colorectal cancer (CRC). Here, we conducted genome-wide DNA methylation analysis of FAP neoplasms, including seven cancer samples and 16 ade...
Autores principales: | Takane, Kiyoko, Fukuyo, Masaki, Matsusaka, Keisuke, Ota, Satoshi, Rahmutulla, Bahityar, Matsushita, Kazuyuki, Miyauchi, Hideaki, Nakatani, Yukio, Matsubara, Hisahiro, Kaneda, Atsushi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135695/ https://www.ncbi.nlm.nih.gov/pubmed/30220972 http://dx.doi.org/10.18632/oncotarget.25987 |
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