The microRNA miR-21 Is a Mediator of FGF8 Action on Cortical COUP-TFI Translation

The morphogen FGF8 plays a pivotal role in neocortical area patterning through its inhibitory effect on COUP-TFI/Nr2f1 anterior expression, but its mechanism of action is poorly understood. We established an in vitro model of mouse embryonic stem cell corticogenesis in which COUP-TFI protein express...

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Detalles Bibliográficos
Autores principales: Terrigno, Marco, Bertacchi, Michele, Pandolfini, Luca, Baumgart, Mario, Calvello, Mariantonietta, Cellerino, Alessandro, Studer, Michèle, Cremisi, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135738/
https://www.ncbi.nlm.nih.gov/pubmed/30174317
http://dx.doi.org/10.1016/j.stemcr.2018.08.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135738/
https://www.ncbi.nlm.nih.gov/pubmed/30174317
http://dx.doi.org/10.1016/j.stemcr.2018.08.002

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