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The microRNA miR-21 Is a Mediator of FGF8 Action on Cortical COUP-TFI Translation

The morphogen FGF8 plays a pivotal role in neocortical area patterning through its inhibitory effect on COUP-TFI/Nr2f1 anterior expression, but its mechanism of action is poorly understood. We established an in vitro model of mouse embryonic stem cell corticogenesis in which COUP-TFI protein express...

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Detalles Bibliográficos
Autores principales:	Terrigno, Marco, Bertacchi, Michele, Pandolfini, Luca, Baumgart, Mario, Calvello, Mariantonietta, Cellerino, Alessandro, Studer, Michèle, Cremisi, Federico
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135738/ https://www.ncbi.nlm.nih.gov/pubmed/30174317 http://dx.doi.org/10.1016/j.stemcr.2018.08.002

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