The acetylation of cyclin-dependent kinase 5 at lysine 33 regulates kinase activity and neurite length in hippocampal neurons

Cyclin-dependent kinase 5 (CDK5) plays a pivotal role in neural development and neurodegeneration. CDK5 activity can be regulated by posttranslational modifications, including phosphorylation and S-nitrosylation. In this study, we demonstrate a novel mechanism by which the acetylation of CDK5 at K33...

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Detalles Bibliográficos
Autores principales: Lee, Juhyung, Ko, Yeon Uk, Chung, Yuhyun, Yun, Nuri, Kim, Myungjin, Kim, Kyungjin, Oh, Young J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135752/
https://www.ncbi.nlm.nih.gov/pubmed/30209341
http://dx.doi.org/10.1038/s41598-018-31785-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135752/
https://www.ncbi.nlm.nih.gov/pubmed/30209341
http://dx.doi.org/10.1038/s41598-018-31785-9

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