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MIgGGly (mouse IgG glycosylation analysis) - a high-throughput method for studying Fc-linked IgG N-glycosylation in mice with nanoUPLC-ESI-MS

Immunoglobulin G (IgG) N-glycosylation is crucial for its effector functions. It is a complex trait, and large sample sets are needed to discover multiple genetic factors that underlie it. While in humans such high-throughput studies of IgG N-glycans became usual, only one has been carried out in mi...

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Detalles Bibliográficos
Autores principales: Zaytseva, Olga O., Jansen, Bas C., Hanić, Maja, Mrčela, Mia, Razdorov, Genadij, Stojković, Ranko, Erhardt, Julija, Brizić, Ilija, Jonjić, Stipan, Pezer, Marija, Lauc, Gordan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135756/
https://www.ncbi.nlm.nih.gov/pubmed/30209257
http://dx.doi.org/10.1038/s41598-018-31844-1