Autophagy regulates vinorelbine sensitivity due to continued Keap1-mediated ROS generation in lung adenocarcinoma cells

Autophagy is one of the induced mechanisms in metastatic cancer to escape death due to starvation, hypoxia, metabolic stresses, chemotherapy, and radiation. Some publications have revealed that chemotherapy combined with autophagy inhibitor will overcome drug resistance. We modified AS2 cells with P...

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Detalles Bibliográficos
Autores principales: Wu, Yan-Wei, Lin, Chiou-Feng, Lin, Yee-Shin, Su, Wu-Chou, Chiu, Wei-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135768/
https://www.ncbi.nlm.nih.gov/pubmed/30245856
http://dx.doi.org/10.1038/s41420-018-0098-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135768/
https://www.ncbi.nlm.nih.gov/pubmed/30245856
http://dx.doi.org/10.1038/s41420-018-0098-6

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