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Autophagy regulates vinorelbine sensitivity due to continued Keap1-mediated ROS generation in lung adenocarcinoma cells
Autophagy is one of the induced mechanisms in metastatic cancer to escape death due to starvation, hypoxia, metabolic stresses, chemotherapy, and radiation. Some publications have revealed that chemotherapy combined with autophagy inhibitor will overcome drug resistance. We modified AS2 cells with P...
Autores principales: | Wu, Yan-Wei, Lin, Chiou-Feng, Lin, Yee-Shin, Su, Wu-Chou, Chiu, Wei-Hsin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135768/ https://www.ncbi.nlm.nih.gov/pubmed/30245856 http://dx.doi.org/10.1038/s41420-018-0098-6 |
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