STAT3-coordinated migration facilitates the dissemination of diffuse large B-cell lymphomas

The motile characteristics and mechanisms that drive the dissemination of diffuse large B-cell lymphoma (DLBCL) are elusive. Here, we show that DLBCL initiates dissemination through activating STAT3-mediated amoeboid migration. Mechanistically, STAT3 activates RHOH transcription, which competes with...

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Detalles Bibliográficos
Autores principales: Pan, Yi-Ru, Chen, Chih-Cheng, Chan, Yu-Tien, Wang, Hsiao-Jung, Chien, Fan-Tso, Chen, Yeng-Long, Liu, Jing-Lan, Yang, Muh-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135800/
https://www.ncbi.nlm.nih.gov/pubmed/30209389
http://dx.doi.org/10.1038/s41467-018-06134-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135800/
https://www.ncbi.nlm.nih.gov/pubmed/30209389
http://dx.doi.org/10.1038/s41467-018-06134-z

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