Improved fragment-based protein structure prediction by redesign of search heuristics

Difficulty in sampling large and complex conformational spaces remains a key limitation in fragment-based de novo prediction of protein structure. Our previous work has shown that even for small-to-medium-sized proteins, some current methods inadequately sample alternative structures. We have develo...

Descripción completa

Detalles Bibliográficos
Autores principales: Kandathil, Shaun M., Garza-Fabre, Mario, Handl, Julia, Lovell, Simon C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135816/
https://www.ncbi.nlm.nih.gov/pubmed/30209258
http://dx.doi.org/10.1038/s41598-018-31891-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135816/
https://www.ncbi.nlm.nih.gov/pubmed/30209258
http://dx.doi.org/10.1038/s41598-018-31891-8

Ejemplares similares