Differential HDAC1/2 network analysis reveals a role for prefoldin/CCT in HDAC1/2 complex assembly

HDAC1 and HDAC2 are components of several corepressor complexes (NuRD, Sin3, CoREST and MiDAC) that regulate transcription by deacetylating histones resulting in a more compact chromatin environment. This limits access of transcriptional machinery to genes and silences transcription. While using an...

Descripción completa

Detalles Bibliográficos
Autores principales: Banks, Charles A. S., Miah, Sayem, Adams, Mark K., Eubanks, Cassandra G., Thornton, Janet L., Florens, Laurence, Washburn, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135828/
https://www.ncbi.nlm.nih.gov/pubmed/30209338
http://dx.doi.org/10.1038/s41598-018-32009-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135828/
https://www.ncbi.nlm.nih.gov/pubmed/30209338
http://dx.doi.org/10.1038/s41598-018-32009-w

Ejemplares similares