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Differential HDAC1/2 network analysis reveals a role for prefoldin/CCT in HDAC1/2 complex assembly

HDAC1 and HDAC2 are components of several corepressor complexes (NuRD, Sin3, CoREST and MiDAC) that regulate transcription by deacetylating histones resulting in a more compact chromatin environment. This limits access of transcriptional machinery to genes and silences transcription. While using an...

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Detalles Bibliográficos
Autores principales:	Banks, Charles A. S., Miah, Sayem, Adams, Mark K., Eubanks, Cassandra G., Thornton, Janet L., Florens, Laurence, Washburn, Michael P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135828/ https://www.ncbi.nlm.nih.gov/pubmed/30209338 http://dx.doi.org/10.1038/s41598-018-32009-w

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