Characterization and targeting of malignant stem cells in patients with advanced myelodysplastic syndromes

Myelodysplastic syndrome (MDS) is a chronic hematologic disorder that frequently evolves to more aggressive stages and in some cases leads to acute myeloid leukemia (AML). MDS arises from mutations in hematopoietic stem cells (HSCs). Thus, to define optimal therapies, it is essential to understand m...

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Detalles Bibliográficos
Autores principales: Stevens, Brett M., Khan, Nabilah, D’Alessandro, Angelo, Nemkov, Travis, Winters, Amanda, Jones, Courtney L., Zhang, Wei, Pollyea, Daniel A., Jordan, Craig T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135858/
https://www.ncbi.nlm.nih.gov/pubmed/30209285
http://dx.doi.org/10.1038/s41467-018-05984-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135858/
https://www.ncbi.nlm.nih.gov/pubmed/30209285
http://dx.doi.org/10.1038/s41467-018-05984-x

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