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Stabilization of HIF-2α impacts pancreas growth

Hypoxia inducible factors (HIFs) are critical regulators of the response to oxygen deficiency by activating target genes involved in a variety of biological functions. HIFs have been implicated in the pathophysiology of numerous pathologies including cancer. Patients with mutations in the von Hippel...

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Detalles Bibliográficos
Autores principales: Flores-Martínez, Alvaro, García-Núñez, Alejandro, Rojas, Anabel, Cano, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135861/
https://www.ncbi.nlm.nih.gov/pubmed/30209343
http://dx.doi.org/10.1038/s41598-018-32054-5