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Oxygen Activation Switch in the Copper Amine Oxidase of Escherichia coli

[Image: see text] Copper amine oxidases (CuAOs) are metalloenzymes that reduce molecular oxygen to hydrogen peroxide during catalytic turnover of primary amines. In addition to Cu(2+) in the active site, two peripheral calcium sites, ∼32 Å from the active site, have roles in Escherichia coli amine o...

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Detalles Bibliográficos
Autores principales: Gaule, Thembaninkosi G., Smith, Mark A., Tych, Katarzyna M., Pirrat, Pascale, Trinh, Chi H., Pearson, Arwen R., Knowles, Peter F., McPherson, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136094/
https://www.ncbi.nlm.nih.gov/pubmed/30110143
http://dx.doi.org/10.1021/acs.biochem.8b00633