Genetically determined high activities of the TNF-alpha, IL23/IL17, and NFkB pathways were associated with increased risk of ankylosing spondylitis

BACKGROUND: Ankylosing spondylitis (AS) results from the combined effects of susceptibility genes and environmental factors. Polymorphisms in genes regulating inflammation may explain part of the heritability of AS. METHODS: Using a candidate gene approach in this case-control study, 51 mainly funct...

Descripción completa

Detalles Bibliográficos
Autores principales: Sode, Jacob, Bank, Steffen, Vogel, Ulla, Andersen, Paal Skytt, Sørensen, Signe Bek, Bojesen, Anders Bo, Andersen, Malene Rohr, Brandslund, Ivan, Dessau, Ram Benny, Hoffmann, Hans Jürgen, Glintborg, Bente, Hetland, Merete Lund, Locht, Henning, Heegaard, Niels Henrik, Andersen, Vibeke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136164/
https://www.ncbi.nlm.nih.gov/pubmed/30208882
http://dx.doi.org/10.1186/s12881-018-0680-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136164/
https://www.ncbi.nlm.nih.gov/pubmed/30208882
http://dx.doi.org/10.1186/s12881-018-0680-z

Ejemplares similares