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Sex-specific differences in organic anion transporting polypeptide 1a4 (Oatp1a4) functional expression at the blood–brain barrier in Sprague–Dawley rats

BACKGROUND: Targeting endogenous blood–brain barrier (BBB) transporters such as organic anion transporting polypeptide 1a4 (Oatp1a4) can facilitate drug delivery for treatment of neurological diseases. Advancement of Oatp targeting for optimization of CNS drug delivery requires characterization of s...

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Detalles Bibliográficos
Autores principales: Brzica, Hrvoje, Abdullahi, Wazir, Reilly, Bianca G., Ronaldson, Patrick T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136214/
https://www.ncbi.nlm.nih.gov/pubmed/30208928
http://dx.doi.org/10.1186/s12987-018-0110-9