Cargando…

Sex-specific differences in organic anion transporting polypeptide 1a4 (Oatp1a4) functional expression at the blood–brain barrier in Sprague–Dawley rats

BACKGROUND: Targeting endogenous blood–brain barrier (BBB) transporters such as organic anion transporting polypeptide 1a4 (Oatp1a4) can facilitate drug delivery for treatment of neurological diseases. Advancement of Oatp targeting for optimization of CNS drug delivery requires characterization of s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Brzica, Hrvoje, Abdullahi, Wazir, Reilly, Bianca G., Ronaldson, Patrick T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136214/ https://www.ncbi.nlm.nih.gov/pubmed/30208928 http://dx.doi.org/10.1186/s12987-018-0110-9

Ejemplares similares

Role of Transporters in Central Nervous System Drug Delivery and Blood-Brain Barrier Protection: Relevance to Treatment of Stroke
por: Brzica, Hrvoje, et al.
Publicado: (2017)

Localization of organic anion transporting polypeptide (Oatp) 1a4 and Oatp1c1 at the rat blood-retinal barrier
por: Akanuma, Shin-ichi, et al.
Publicado: (2013)

Organic anion transporting polypeptides OATP1B1 and OATP1B3 and their genetic variants influence the pharmacokinetics and pharmacodynamics of raloxifene
por: Trdan Lušin, Tina, et al.
Publicado: (2012)

Regulation of Organic Anion Transporting Polypeptides (OATP) 1B1- and OATP1B3-Mediated Transport: An Updated Review in the Context of OATP-Mediated Drug-Drug Interactions
por: Alam, Khondoker, et al.
Publicado: (2018)

Characterization of tick organic anion transporting polypeptides (OATPs) upon bacterial and viral infections
por: Taank, Vikas, et al.
Publicado: (2018)

The involvement of human organic anion transporting polypeptides (OATPs) in drug-herb/food interactions
por: Ali, Youmna, et al.
Publicado: (2020)

Neurosteroids: Structure-Uptake Relationships and Computational Modeling of Organic Anion Transporting Polypeptides (OATP)1A2
por: Adla, Santosh Kumar, et al.
Publicado: (2021)

Organic Anion Transporting Polypeptide 3A1 (OATP3A1)-Gated Bio-Orthogonal Labeling of Intracellular Proteins
por: Németh, Krisztina, et al.
Publicado: (2023)

Identification of Novel Inhibitors of Organic Anion Transporting Polypeptides 1B1 and 1B3 (OATP1B1 and OATP1B3) Using a Consensus Vote of Six Classification Models
por: Kotsampasakou, Eleni, et al.
Publicado: (2015)

Targeting Glial Cells by Organic Anion-Transporting Polypeptide 1C1 (OATP1C1)-Utilizing l-Thyroxine-Derived Prodrugs
por: Tonduru, Arun Kumar, et al.
Publicado: (2023)

Classification of Inhibitors of Hepatic Organic Anion Transporting Polypeptides (OATPs): Influence of Protein Expression on Drug–Drug Interactions
por: Karlgren, Maria, et al.
Publicado: (2012)

Organic anion transporting polypeptide 1B3 (OATP1B3) is overexpressed in colorectal tumors and is a predictor of clinical outcome
por: Lockhart, Albert Craig, et al.
Publicado: (2008)

Organic Anion Transporting Polypeptide (OATP) 1B3 is a Significant Transporter for Hepatic Uptake of Conjugated Bile Acids in Humans
por: Pan, Qiong, et al.
Publicado: (2023)

Single-cell image analysis reveals over-expression of organic anion transporting polypeptides (OATPs) in human glioblastoma tissue
por: Cooper, Elizabeth, et al.
Publicado: (2022)

Developmental deltamethrin: Sex-specific hippocampal effects in Sprague Dawley rats
por: Pitzer, Emily M., et al.
Publicado: (2022)

Treatment with proteasome inhibitor bortezomib decreases organic anion transporting polypeptide (OATP) 1B3-mediated transport in a substrate-dependent manner
por: Alam, Khondoker, et al.
Publicado: (2017)

Organic Anion Transporting Polypeptide 5A1 (OATP5A1) in Small Cell Lung Cancer (SCLC) Cells: Possible Involvement in Chemoresistance to Satraplatin
por: Olszewski-Hamilton, U., et al.
Publicado: (2011)

Organic Anion Transporting Polypeptide 2B1 (OATP2B1) Genetic Variants: In Vitro Functional Characterization and Association With Circulating Concentrations of Endogenous Substrates
por: Medwid, Samantha, et al.
Publicado: (2021)

Ovarian neoplasia in the Sprague-Dawley rat.
por: Lewis, D J
Publicado: (1987)

Hematoxicity of Amodiaquine in Sprague-Dawley Rats
por: Saka, W. A., et al.
Publicado: (2012)

Keishibukuryogan is not carcinogenic in Sprague-Dawley rats
por: Kanitani, Masanao, et al.
Publicado: (2016)

PDZK1 and NHERF1 Regulate the Function of Human Organic Anion Transporting Polypeptide 1A2 (OATP1A2) by Modulating Its Subcellular Trafficking and Stability
por: Zheng, Jian, et al.
Publicado: (2014)

Potential Risk of Food-Drug Interactions: Citrus Polymethoxyflavones and Flavanones as Inhibitors of the Organic Anion Transporting Polypeptides (OATP) 1B1, 1B3, and 2B1
por: Bajraktari-Sylejmani, Gzona, et al.
Publicado: (2020)

Brain Delivery of a Potent Opioid Receptor Agonist, Biphalin during Ischemic Stroke: Role of Organic Anion Transporting Polypeptide (OATP)
por: Albekairi, Thamer H, et al.
Publicado: (2019)

Identification of novel cell-impermeant fluorescent substrates for testing the function and drug interaction of Organic Anion-Transporting Polypeptides, OATP1B1/1B3 and 2B1
por: Patik, Izabel, et al.
Publicado: (2018)

Subchronic Hepatotoxicity Evaluation of 2,3,4,6-Tetrachlorophenol in Sprague Dawley Rats
por: Dodd, Darol E., et al.
Publicado: (2012)

Bamboo salt attenuates CCl(4)-induced hepatic damage in Sprague-Dawley rats
por: Zhao, Xin, et al.
Publicado: (2013)

Inhalation toxicity and carcinogenicity of 1,3-butadiene in Sprague-Dawley rats.
por: Owen, P E, et al.
Publicado: (1990)

Sex differences in the expression of the endocannabinoid system within V1M cortex and PAG of Sprague Dawley rats
por: Levine, Aidan, et al.
Publicado: (2021)

Sex Differences in the Reinstatement of Methamphetamine Seeking after Forced Abstinence in Sprague-Dawley Rats
por: Ruda-Kucerova, Jana, et al.
Publicado: (2015)

Sex Differences in Intestinal P-Glycoprotein Expression in Wistar versus Sprague Dawley Rats
por: Madla, Christine M., et al.
Publicado: (2022)

Effects of different doses and serotypes of LPS on blood-brain barrier permeability in Sprague-Dawley rats
por: Senturk, E, et al.
Publicado: (2013)

Structure of human drug transporters OATP1B1 and OATP1B3
por: Ciută, Anca-Denise, et al.
Publicado: (2023)

Use of Indocyanine Green (ICG), a Medical Near Infrared Dye, for Enhanced Fluorescent Imaging—Comparison of Organic Anion Transporting Polypeptide 1B3 (OATP1B3) and Sodium-Taurocholate Cotransporting Polypeptide (NTCP) Reporter Genes
por: Wu, Menq-Rong, et al.
Publicado: (2019)

Effects of Sex, Age, and Fasting Conditions on Plasma Lipidomic Profiles of Fasted Sprague-Dawley Rats
por: Saito, Kosuke, et al.
Publicado: (2014)

Sex differences in cardiac and renal responses to a high salt diet in Sprague-Dawley rats
por: Oloyo, Ahmed Kolade, et al.
Publicado: (2019)

Cutaneous Hybrid Cyst in a Sprague-Dawley Rat
por: Yasuno, Kyohei, et al.
Publicado: (2012)

Intratubular Spermatocytic Seminomas in 2 Sprague-Dawley Rats
por: Ishigami, Noriaki, et al.
Publicado: (2014)

Reproductive and Developmental Toxicity of Amitraz in Sprague-Dawley Rats
por: Lim, Jeong-Hyeon, et al.
Publicado: (2010)

Splenic Hemangiosarcoma in a Young Sprague-Dawley Rat
por: Shiraki, Katsuhisa, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_9l960pdi92vt62s7u8fs8s6ar9