Distinct Roles for Bruton's Tyrosine Kinase in B Cell Immune Synapse Formation

Bruton's tyrosine kinase (Btk) has a key role in the signaling pathways of receptors essential for the B lymphocyte response. Given its implication in B cell-related immunodeficiencies, leukemias/lymphomas and autoimmunity, Btk is studied intensely and is a target for therapy. Here, using prima...

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Detalles Bibliográficos
Autores principales: Roman-Garcia, Sara, Merino-Cortes, Sara V., Gardeta, Sofia R., de Bruijn, Marjolein J. W., Hendriks, Rudi W., Carrasco, Yolanda R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136277/
https://www.ncbi.nlm.nih.gov/pubmed/30237801
http://dx.doi.org/10.3389/fimmu.2018.02027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136277/
https://www.ncbi.nlm.nih.gov/pubmed/30237801
http://dx.doi.org/10.3389/fimmu.2018.02027

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