Design, synthesis, and screening of ortho-amino thiophene carboxamide derivatives on hepatocellular carcinomaas VEGFR-2Inhibitors

In this work, design, synthesis, and screening of thiophene carboxamides 4–13 and 16–23 as dual vascular endothelial growth factor receptors (VEGFRs) and mitotic inhibitors was reported. All compounds were screened against two gastrointestinal solid cancer cells, HepG-2 and HCT-116 cell lines. The m...

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Detalles Bibliográficos
Autores principales: AbdElhameid, Mohammed K., Labib, Madlen B., Negmeldin, Ahmed T., Al-Shorbagy, Muhammad, Mohammed, Manal R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136361/
https://www.ncbi.nlm.nih.gov/pubmed/30191744
http://dx.doi.org/10.1080/14756366.2018.1503654

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136361/
https://www.ncbi.nlm.nih.gov/pubmed/30191744
http://dx.doi.org/10.1080/14756366.2018.1503654

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