The protective effects of rapamycin on cell autophagy in the renal tissues of rats with diabetic nephropathy via mTOR-S6K1-LC3II signaling pathway

Background: Previous studies have shown that podocyte autophagy is an important trigger for proteinuria and glomerulosclerosis. The mammalian rapamycin target protein (mTOR) occupies a pivotal position in the autophagy pathway. In this study, we planned to clarify the mechanism of mTOR regulation of...

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Detalles Bibliográficos
Autores principales: Liu, Lei, Yang, Lijuan, Chang, Baochao, Zhang, Jiqiang, Guo, Yaling, Yang, Xiangdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Laboratory Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136383/
https://www.ncbi.nlm.nih.gov/pubmed/30200803
http://dx.doi.org/10.1080/0886022X.2018.1489287

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136383/
https://www.ncbi.nlm.nih.gov/pubmed/30200803
http://dx.doi.org/10.1080/0886022X.2018.1489287

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