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The protective effects of rapamycin on cell autophagy in the renal tissues of rats with diabetic nephropathy via mTOR-S6K1-LC3II signaling pathway

Background: Previous studies have shown that podocyte autophagy is an important trigger for proteinuria and glomerulosclerosis. The mammalian rapamycin target protein (mTOR) occupies a pivotal position in the autophagy pathway. In this study, we planned to clarify the mechanism of mTOR regulation of...

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Detalles Bibliográficos
Autores principales:	Liu, Lei, Yang, Lijuan, Chang, Baochao, Zhang, Jiqiang, Guo, Yaling, Yang, Xiangdong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2018
Materias:	Laboratory Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136383/ https://www.ncbi.nlm.nih.gov/pubmed/30200803 http://dx.doi.org/10.1080/0886022X.2018.1489287

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