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Coptisine-induced inhibition of Helicobacter pylori: elucidation of specific mechanisms by probing urease active site and its maturation process

In this study, we examined the anti-Helicobactor pylori effects of the main protoberberine-type alkaloids in Rhizoma Coptidis. Coptisine exerted varying antibacterial and bactericidal effects against three standard H. pylori strains and eleven clinical isolates, including four drug-resistant strains...

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Detalles Bibliográficos
Autores principales: Li, Cailan, Huang, Ping, Wong, Kambo, Xu, Yifei, Tan, Lihua, Chen, Hanbin, Lu, Qiang, Luo, Chaodan, Tam, Chunlai, Zhu, Lixiang, Su, Ziren, Xie, Jianhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136390/
https://www.ncbi.nlm.nih.gov/pubmed/30191728
http://dx.doi.org/10.1080/14756366.2018.1501044