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Nucleosides isolated from Ophiocordyceps sinensis inhibit cigarette smoke extract-induced inflammation via the SIRT1–nuclear factor-κB/p65 pathway in RAW264.7 macrophages and in COPD mice

BACKGROUND: Ophiocordyceps sinensis (C. sinensis) extracts have been found to have a therapeutic effect on patients with chronic obstructive pulmonary disease (COPD). Silent information regulator 1 (SIRT1) plays an important role in the regulation of inflammatory mediators and correlates with lung f...

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Detalles Bibliográficos
Autores principales: Sun, Xiao, Dong, Zhonghua, Li, Nan, Feng, Xiuli, Liu, Yan, Li, Ang, Zhu, Xiaosong, Li, Chunyan, Zhao, Zhongxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136406/
https://www.ncbi.nlm.nih.gov/pubmed/30237706
http://dx.doi.org/10.2147/COPD.S172579