Molecular Analysis and Modeling of Hepatitis E Virus Helicase and Identification of Novel Inhibitors by Virtual Screening

The hepatitis E virus- (HEV-) helicase as a novel drug-target was evaluated. While cell culture model was used for mutational characterization of helicase, in silico protein modeling and virtual screening were employed to identify helicase inhibitors. None of the saturation mutant replicons signific...

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Detalles Bibliográficos
Autores principales: Parvez, Mohammad K., Subbarao, Naidu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136533/
https://www.ncbi.nlm.nih.gov/pubmed/30246023
http://dx.doi.org/10.1155/2018/5753804

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136533/
https://www.ncbi.nlm.nih.gov/pubmed/30246023
http://dx.doi.org/10.1155/2018/5753804

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