Cargando…

Modeling of xenobiotic transport and metabolism in virtual hepatic lobule models

Computational models of normal liver function and xenobiotic induced liver damage are increasingly being used to interpret in vitro and in vivo data and as an approach to the de novo prediction of the liver’s response to xenobiotics. The microdosimetry (dose at the level of individual cells) of xeno...

Descripción completa

Detalles Bibliográficos
Autores principales: Fu, Xiao, Sluka, James P., Clendenon, Sherry G., Dunn, Kenneth W., Wang, Zemin, Klaunig, James E., Glazier, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136710/
https://www.ncbi.nlm.nih.gov/pubmed/30212461
http://dx.doi.org/10.1371/journal.pone.0198060