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Modeling of xenobiotic transport and metabolism in virtual hepatic lobule models
Computational models of normal liver function and xenobiotic induced liver damage are increasingly being used to interpret in vitro and in vivo data and as an approach to the de novo prediction of the liver’s response to xenobiotics. The microdosimetry (dose at the level of individual cells) of xeno...
Autores principales: | Fu, Xiao, Sluka, James P., Clendenon, Sherry G., Dunn, Kenneth W., Wang, Zemin, Klaunig, James E., Glazier, James A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136710/ https://www.ncbi.nlm.nih.gov/pubmed/30212461 http://dx.doi.org/10.1371/journal.pone.0198060 |
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