PPARα-mediated peroxisome induction compensates PPARγ-deficiency in bronchiolar club cells

Despite the important functions of PPARγ in various cell types of the lung, PPARγ-deficiency in club cells induces only mild emphysema. Peroxisomes are distributed in a similar way as PPARγ in the lung and are mainly enriched in club and AECII cells. To date, the effects of PPARγ-deficiency on the o...

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Detalles Bibliográficos
Autores principales: Karnati, Srikanth, Oruqaj, Gani, Janga, Harshavardhan, Tumpara, Srinu, Colasante, Claudia, Van Veldhoven, Paul P., Braverman, Nancy, Pilatz, Adrian, Mariani, Thomas J., Baumgart-Vogt, Eveline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136741/
https://www.ncbi.nlm.nih.gov/pubmed/30212482
http://dx.doi.org/10.1371/journal.pone.0203466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136741/
https://www.ncbi.nlm.nih.gov/pubmed/30212482
http://dx.doi.org/10.1371/journal.pone.0203466

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