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Antenatal exposure to betamethasone induces placental 11β-hydroxysteroid dehydrogenase type 2 expression and the adult metabolic disorders in mice

Antenatal overexposure to glucocorticoids causes fetal intrauterine growth restriction (IUGR) and adult metabolic disorders. 11β-hydroxysteroid dehydrogenase (11β-HSD) 1 and 2 are key enzymes for glucocorticoid metabolism, however, the detailed effects of antenatal overexposure to glucocorticoids on...

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Detalles Bibliográficos
Autores principales: Ni, Li, Pan, Yibin, Tang, Chao, Xiong, Wenyi, Wu, Ximei, Zou, Chaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136781/
https://www.ncbi.nlm.nih.gov/pubmed/30212527
http://dx.doi.org/10.1371/journal.pone.0203802