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Optimization of the Cohesion Index in the SeDeM Diagram Expert System and application of SeDeM Diagram: An improved methodology to determine the Cohesion Index

In this study, we suggest optimizing the methodology to determine the Cohesion Index (Icd) in order to avoid mistaken characterizations due to powder bulk density. For this purpose, five different excipients, with different bulk densities and of different chemical nature, were compressed at differen...

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Detalles Bibliográficos
Autores principales: Nofrerias, Isaac, Nardi, Anna, Suñé-Pou, Marc, Boeckmans, Joost, Suñé-Negre, Josep Maria, García-Montoya, Encarna, Pérez-Lozano, Pilar, Ticó-Grau, Josep Ramón, Miñarro-Carmona, Montserrat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136784/
https://www.ncbi.nlm.nih.gov/pubmed/30212557
http://dx.doi.org/10.1371/journal.pone.0203846