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Randomized study of doxorubicin-based chemotherapy regimens, with and without sildenafil, with analysis of intermediate cardiac markers

BACKGROUND: Doxorubicin chemotherapy is used across a range of adult and pediatric malignancies. Cardiac toxicity is common, and dysfunction develops over time in many patients. Biomarkers used for predicting late cardiac dysfunction following doxorubicin exposure have shown promise. Preclinical stu...

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Detalles Bibliográficos
Autores principales: Poklepovic, Andrew, Qu, Yuesheng, Dickinson, Molly, Kontos, Michael C., Kmieciak, Maciej, Schultz, Elizabeth, Bandopadhyay, Dipankar, Deng, Xiaoyan, Kukreja, Rakesh C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136838/
https://www.ncbi.nlm.nih.gov/pubmed/30221011
http://dx.doi.org/10.1186/s40959-018-0033-2