Chemokine receptor engineering of T cells with CXCR2 improves homing towards subcutaneous human melanomas in xenograft mouse model

Adoptive cell therapy (ACT) using in vitro expanded tumor infiltrating T lymphocytes (TILs) from biopsy material represents a highly promising treatment of disseminated cancer. A crucial prerequisite for successful ACT is sufficient recruitment of transferred lymphocytes to the tumor site; however,...

Descripción completa

Detalles Bibliográficos
Autores principales: Idorn, Manja, Skadborg, Signe Koggersbøl, Kellermann, Lauge, Halldórsdóttir, Hólmfrídur Rósa, Holmen Olofsson, Gitte, Met, Özcan, thor Straten, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136860/
https://www.ncbi.nlm.nih.gov/pubmed/30221044
http://dx.doi.org/10.1080/2162402X.2018.1450715

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136860/
https://www.ncbi.nlm.nih.gov/pubmed/30221044
http://dx.doi.org/10.1080/2162402X.2018.1450715

Ejemplares similares