Cell-type specific MyD88 signaling is required for intestinal tumor initiation and progression to malignancy

The signal adapter MyD88, an essential component of Toll-like receptor (TLR) signaling, is important for gut-microbiome interactions. However, its contribution to cancer and its cell-type specific functions are controversially discussed. Therefore, we generated new tissue-specific mouse models and a...

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Detalles Bibliográficos
Autores principales: Holtorf, Anne, Conrad, Anja, Holzmann, Bernhard, Janssen, Klaus-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136867/
https://www.ncbi.nlm.nih.gov/pubmed/30221070
http://dx.doi.org/10.1080/2162402X.2018.1466770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136867/
https://www.ncbi.nlm.nih.gov/pubmed/30221070
http://dx.doi.org/10.1080/2162402X.2018.1466770

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