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Driving Natural Killer cells toward the melanoma tumor battlefield: Autophagy as a valuable therapeutic target

Natural Killer (NK) cell-based cancer immunotherapies were often disappointing in the clinic mostly due to insufficient NK cell infiltration into tumors. We found that targeting autophagy induced a massive infiltration of NK cells into melanoma tumors. These findings highlight autophagy inhibition a...

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Detalles Bibliográficos
Autores principales: Noman, Muhammad Zaeem, Paggetti, Jerome, Moussay, Etienne, Berchem, Guy, Janji, Bassam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136884/
https://www.ncbi.nlm.nih.gov/pubmed/30221048
http://dx.doi.org/10.1080/2162402X.2018.1452583