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Synthesis of multivalent polymer–aptamer conjugates with enhanced inhibitory potency
PURPOSE: We are interested in designing a modular strategy for creating potent multivalent ligands, which frequently can be used as effective inhibitors of undesired biomolecular interactions. For example, such inhibitors might prevent the self-assembly of bacterial toxins or the attachment of a vir...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136935/ https://www.ncbi.nlm.nih.gov/pubmed/30237711 http://dx.doi.org/10.2147/IJN.S174673 |