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Synthesis of multivalent polymer–aptamer conjugates with enhanced inhibitory potency

PURPOSE: We are interested in designing a modular strategy for creating potent multivalent ligands, which frequently can be used as effective inhibitors of undesired biomolecular interactions. For example, such inhibitors might prevent the self-assembly of bacterial toxins or the attachment of a vir...

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Detalles Bibliográficos
Autores principales: Martin, Jacob T, Douaisi, Marc, Arsiwala, Ammar, Arha, Manish, Kane, Ravi S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136935/
https://www.ncbi.nlm.nih.gov/pubmed/30237711
http://dx.doi.org/10.2147/IJN.S174673