An Early Function of Polycystin-2 for Left-Right Organizer Induction in Xenopus

Nodal signaling controls asymmetric organ placement during vertebrate embryogenesis. Nodal is induced by a leftward fluid flow at the ciliated left-right organizer (LRO). The mechanism of flow sensing, however, has remained elusive. pkd2 encodes the calcium channel Polycystin-2, which is required fo...

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Detalles Bibliográficos
Autores principales: Vick, Philipp, Kreis, Jennifer, Schneider, Isabelle, Tingler, Melanie, Getwan, Maike, Thumberger, Thomas, Beyer, Tina, Schweickert, Axel, Blum, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136938/
https://www.ncbi.nlm.nih.gov/pubmed/30428378
http://dx.doi.org/10.1016/j.isci.2018.03.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136938/
https://www.ncbi.nlm.nih.gov/pubmed/30428378
http://dx.doi.org/10.1016/j.isci.2018.03.011

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