Cargando…

An Early Function of Polycystin-2 for Left-Right Organizer Induction in Xenopus

Nodal signaling controls asymmetric organ placement during vertebrate embryogenesis. Nodal is induced by a leftward fluid flow at the ciliated left-right organizer (LRO). The mechanism of flow sensing, however, has remained elusive. pkd2 encodes the calcium channel Polycystin-2, which is required fo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vick, Philipp, Kreis, Jennifer, Schneider, Isabelle, Tingler, Melanie, Getwan, Maike, Thumberger, Thomas, Beyer, Tina, Schweickert, Axel, Blum, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136938/ https://www.ncbi.nlm.nih.gov/pubmed/30428378 http://dx.doi.org/10.1016/j.isci.2018.03.011

Ejemplares similares

Connexin26-mediated transfer of laterality cues in Xenopus
por: Beyer, Tina, et al.
Publicado: (2012)

dmrt2 and myf5 Link Early Somitogenesis to Left-Right Axis Determination in Xenopus laevis
por: Tingler, Melanie, et al.
Publicado: (2022)

Wnt11b Is Involved in Cilia-Mediated Symmetry Breakage during Xenopus Left-Right Development
por: Walentek, Peter, et al.
Publicado: (2013)

Bicc1 and Dicer regulate left-right patterning through post-transcriptional control of the Nodal inhibitor Dand5
por: Maerker, Markus, et al.
Publicado: (2021)

A novel role of the organizer gene Goosecoid as an inhibitor of Wnt/PCP-mediated convergent extension in Xenopus and mouse
por: Ulmer, Bärbel, et al.
Publicado: (2017)

Vertebrate Left-Right Asymmetry: What Can Nodal Cascade Gene Expression Patterns Tell Us?
por: Schweickert, Axel, et al.
Publicado: (2017)

Cilia are required for asymmetric nodal induction in the sea urchin embryo
por: Tisler, Matthias, et al.
Publicado: (2016)

FGF-mediated establishment of left-right asymmetry requires Rab7 function in the dorsal mesoderm in Xenopus
por: Kreis, Jennifer, et al.
Publicado: (2022)

ATP4 and ciliation in the neuroectoderm and endoderm of Xenopus embryos and tadpoles
por: Walentek, Peter, et al.
Publicado: (2015)

Ciliary and non-ciliary expression and function of PACRG during vertebrate development
por: Thumberger, Thomas, et al.
Publicado: (2012)

Serotonin and ATP4 are required for Wnt signaling and cilia-driven leftward flow in Xenopus
por: Blum, M, et al.
Publicado: (2012)

Expression and cilia associated localization of Histone deacetylases 6 in Xenopus
por: Tisler, Matthias, et al.
Publicado: (2023)

The tetraspanin Cd63 is required for eye morphogenesis in Xenopus
por: Kreis, Jennifer, et al.
Publicado: (2020)

Rab7 is required for mesoderm patterning and gastrulation in Xenopus
por: Kreis, Jennifer, et al.
Publicado: (2021)

Expression of an endosome-excluded Cd63 prevents axis elongation in Xenopus
por: Kreis, Jennifer, et al.
Publicado: (2020)

The ion channel function of polycystin‐1 in the polycystin‐1/polycystin‐2 complex
por: Wang, Zhifei, et al.
Publicado: (2019)

A polycystin-centric view of cyst formation and disease: the polycystins revisited
por: Ong, Albert CM, et al.
Publicado: (2015)

Polycystins and mechanotransduction in bone
por: Gargalionis, Antonios N., et al.
Publicado: (2017)

Polycystins in Colorectal Cancer
por: Gargalionis, Antonios N., et al.
Publicado: (2018)

Low Frequency Vibrations Disrupt Left-Right Patterning in the Xenopus Embryo
por: Vandenberg, Laura N., et al.
Publicado: (2011)

Polycystins and Mechanotransduction in Human Disease
por: Gargalionis, Antonios N., et al.
Publicado: (2019)

Polycystins, ADPKD, and Cardiovascular Disease
por: Kuo, Ivana Y., et al.
Publicado: (2019)

Polycystins, mechanotransduction and cancer development
por: Papavassiliou, Kostas A., et al.
Publicado: (2022)

A polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexes
por: Giamarchi, Aurélie, et al.
Publicado: (2010)

A plasma membrane-localized polycystin-1/polycystin-2 complex in endothelial cells elicits vasodilation
por: MacKay, Charles E, et al.
Publicado: (2022)

Polycystin-1 Interacting Protein-1 (CU062) Interacts with the Ectodomain of Polycystin-1 (PC1)
por: Lea, Wendy A., et al.
Publicado: (2023)

Serotonin has early, cilia-independent roles in Xenopus left-right patterning
por: Vandenberg, Laura N., et al.
Publicado: (2013)

Genetic Analysis Reveals a Hierarchy of Interactions between Polycystin-Encoding Genes and Genes Controlling Cilia Function during Left-Right Determination
por: Grimes, Daniel T., et al.
Publicado: (2016)

Polycystins and cellular Ca(2+) signaling
por: Mekahli, D., et al.
Publicado: (2012)

Polycystin-2 Associates With Malignancy in Meningiomas
por: Assimakopoulou, Martha, et al.
Publicado: (2023)

Energetic landscape of polycystin channel gating
por: Ng, Leo CT, et al.
Publicado: (2023)

Polycystin-1 Surface Localization Is Stimulated by Polycystin-2 and Cleavage at the G Protein-coupled Receptor Proteolytic Site
por: Chapin, Hannah C., et al.
Publicado: (2010)

Ciliogenesis and cerebrospinal fluid flow in the developing Xenopus brain are regulated by foxj1
por: Hagenlocher, Cathrin, et al.
Publicado: (2013)

Nodal signalling in Xenopus: the role of Xnr5 in left/right asymmetry and heart development
por: Tadjuidje, Emmanuel, et al.
Publicado: (2016)

Candidate Heterotaxy Gene FGFR4 Is Essential for Patterning of the Left-Right Organizer in Xenopus
por: Sempou, Emily, et al.
Publicado: (2018)

Neural Induction without Mesoderm in Xenopus
Publicado: (2004)

Identification of Polycystin-2 and CFTR common targets
por: Roxo-Rosa, M, et al.
Publicado: (2015)

Regulation of Polycystin-1 Function by Calmodulin Binding
por: Doerr, Nicholas, et al.
Publicado: (2016)

Structural Interaction and Functional Regulation of Polycystin-2 by Filamin
por: Wang, Qian, et al.
Publicado: (2012)

Intracellular calcium release modulates polycystin-2 trafficking
por: Miyakawa, Ayako, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_ass4c13hfs8ej1s2nqhejugjcf