Shared and independent functions of aPKCλ and Par3 in skin tumorigenesis

The polarity proteins Par3 and aPKC are key regulators of processes altered in cancer. Par3/aPKC are thought to dynamically interact with Par6 but increasing evidence suggests that aPKC and Par3 also exert complex-independent functions. Whereas aPKCλ serves as tumor promotor, Par3 can either promote...

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Detalles Bibliográficos
Autores principales: Vorhagen, Susanne, Kleefisch, Dominik, Persa, Oana-Diana, Graband, Annika, Schwickert, Alexandra, Saynisch, Michael, Leitges, Michael, Niessen, Carien M., Iden, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137026/
https://www.ncbi.nlm.nih.gov/pubmed/29789715
http://dx.doi.org/10.1038/s41388-018-0313-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137026/
https://www.ncbi.nlm.nih.gov/pubmed/29789715
http://dx.doi.org/10.1038/s41388-018-0313-1

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