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Crystal structure of TcpK in complex with oriT DNA of the antibiotic resistance plasmid pCW3

Conjugation is fundamental for the acquisition of new genetic traits and the development of antibiotic resistance in pathogenic organisms. Here, we show that a hypothetical Clostridium perfringens protein, TcpK, which is encoded by the tetracycline resistance plasmid pCW3, is essential for efficient...

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Detalles Bibliográficos
Autores principales: Traore, Daouda A. K., Wisniewski, Jessica A., Flanigan, Sarena F., Conroy, Paul J., Panjikar, Santosh, Mok, Yee-Foong, Lao, Carmen, Griffin, Michael D. W., Adams, Vicki, Rood, Julian I., Whisstock, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137059/
https://www.ncbi.nlm.nih.gov/pubmed/30213934
http://dx.doi.org/10.1038/s41467-018-06096-2